BS-181
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13266-10 mM * 1 mL |
| CAS # | 1092443-52-1 |
| Pricing | 10 mM * 1 mL, USD $121.0 |
| Biological Activity | BS-181 is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880, 3000 and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 inhibits a panel of cancer cells growth (IC50=11.5 μM-37.3 μM) and induces cell apoptosis. BS-181 has the potential for the research of cancer therapy[1][2]. |
| Purity | 98.10% |
| MWt | 380.53 |
| Formula | C₂₂H₃₂N₆ |