RG108
Supplier | MedChemExpress |
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Product # | HY-13642-10 mM * 1 mL |
CAS # | 48208-26-0 |
Pricing | 10 mM * 1 mL, USD $79.0 |
Synonyms | N-Phthalyl-L-tryptophan |
MWt | 334.33 |
Formula | C₁₉H₁₄N₂O₄ |
Biological Activity | RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences[1][2][3]. |
Purity | 99.81% |