K-Ras ligand-Linker Conjugate 4
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130822-100 mg |
| CAS # | 2378261-83-5 |
| Pricing | 100 mg, USD $800.0 |
| Biological Activity | K-Ras ligand-Linker Conjugate 4 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 4 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells[1]. |
| MWt | 697.82 |
| Formula | C₃₅H₅₁N₇O₈ |