| Supplier |
Creative Peptides |
| Product # |
A19007 |
| Pricing |
Inquire
|
| MolecularWeight |
853.1
|
| Sequence |
- One Letter Code: FKP-(D-Cha)-Cha-r
- Three Letter Code: H-Phe-Lys-Pro-D-Cha-Cha-D-Arg-OH
|
| Storage |
-20°C
|
| Explanation |
This peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions as a C5a receptor agonist. C5a is a plasma protein involved in cellular inflammatory processes by inducing chemotaxis, degranulation of leukocytes, increased vascular permeability, and cytokine production. The cyclohexylalanine at position 5 is crucial to agonist function. Arg at the last position is of the d-isomer.
|
| Reference |
Buck, E. et al. PNAS 102, 2719 (2005); Higginbottom, A. J Biol Chem 280, 17831 (2005).
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