Methoxyluteolin
Methoxyluteolin inhibits release of pro-inflammatory mediators from mast cells and decreases gene expression and release of TNF, VEGF and IL-8/CXCL8. The product also significantly inhibits IL-33 stimulated expression and release of CCL5 and CCL2. Methoxyluteolin pretreatment of LAD2 mast cells decreases gene expression of TNF, CXCL8 and VEGF in response to neurotensin or substance P via mTOR activation.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD514 |
| CAS # | 855-97-0 |
| Pricing | Customizable size, Inquiry |
| Synonym | Methoxyluteolin; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H18O6 |
| Exact Mass | 342.11 |
| Molecular Weight | 342.35 |
| Elemental Analysis | C, 66.66; H, 5.30; O, 28.04 |
| IUPAC/Chemical Name | 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4H-1-benzopyran-4-one |
| InChi Key | CLXVBVLQKLQNRQ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H18O6/c1-21-12-8-17(24-4)19-13(20)10-15(25-18(19)9-12)11-5-6-14(22-2)16(7-11)23-3/h5-10H,1-4H3 |
| SMILES Code | O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(OC)=CC(OC)=C13 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |