Raphin1 acetate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-123960A-10 mg |
| CAS # | 2242616-04-0 |
| Pricing | 10 mg, USD $125.0 |
| Biological Activity | Raphin1 acetate is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). Raphin1 acetate binds strongly to the R15B-PP1c holophosphatase (Kd=33 nM), and shows ~30-fold selective in binding R15B-PP1c over R15A-PP1c. Raphin1 acetate crosses the blood-brain barrier, and reduces organismal and molecular deficits in a mouse model of a protein misfolding disease[1]. |
| Purity | 99.22% |
| MWt | 291.13 |
| Formula | C₁₀H₁₂Cl₂N₄O₂ |