Mouse p21Cip1 Antibody

May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity).
Supplier Abbexa Ltd.
Product # abx034761-400UL
Pricing 400 µl USD $601.75
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications ELISA, WB
UniProt Primary AC P39689
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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