tri-GalNAc-PEG3-Biotin
| Supplier | Alfa Chemistry |
|---|---|
| Product # | ACMA00049966 |
| CAS # | |
| Pricing | Inquire |
| Synonyms | tris-GalNAc-β-Ala-PEG3-Biotin, tri-GalNAc-β-Ala-PEG3-Biotin, (β-GalNAc)3-sp-β-Ala-PEG3-Biotin, (β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-NH-Biotin, triantennary β-D-GalNAc-β-Alanine-PEG3-Biotin |
| Purity | ≥90% (HPLC) |
| MolecularFormula | C83H146N14O34S |
| MolecularWeight | 1916.2 |
| Application | tri-GalNAc-biotin is a biotinylated asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development, comprising a triantennary N-acetylgalactosamine (GalNAc) joined by a PEG linker to biotin. tri-GalNAc-biotin can induce ASGPR-mediated endocytosis and trafficking of fluorescently labeled neutravidin for lysosomal degradation in HepG2 cells in a time-dependent manner. |