Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) Antibody
SLAMF1 Antibody is a Rabbit Polyclonal antibody against SLAMF1. Following occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cells. SLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAM. Mutations of the SAP gene may be associated with X-linked lympho-proliferative disease (XLP).
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx001661-20UL |
| Pricing | 20 µl USD $203.0 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | WB |
| UniProt Primary AC | Q13291 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |