UNC9975
UNC9975 is a novel β-arrestin-biased D2R agonist. UNC9975 is an analog of aripiprazole and is a β-arrestin–biased dopamine D2 receptor ligand. Functionally selective, β-arrestin-biased D(2)R ligands represent valuable chemical probes for further investigations of D(2)R signaling in health and disease.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1726 |
| CAS # | 1354030-19-5 |
| Pricing | Customizable size, Inquiry |
| Synonym | UNC9975, UNC-9975, UNC9975 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C23H28Cl2N4O2 |
| Exact Mass | 462.1589 |
| Molecular Weight | 463.403 |
| Elemental Analysis | C, 59.61; H, 6.09; Cl, 15.30; N, 12.09; O, 6.91 |
| IUPAC/Chemical Name | 7-{4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy}-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one |
| InChi Key | JQSRFMXTGAVHIR-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C23H28Cl2N4O2/c24-18-5-3-6-19(22(18)25)29-13-4-12-28(14-15-29)11-1-2-16-31-21-10-8-17-7-9-20(30)26-23(17)27-21/h3,5-6,8,10H,1-2,4,7,9,11-16H2,(H,26,27,30) |
| SMILES Code | O=C1NC2=NC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CCC3)=CC=C2CC1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |