SirReal1-O-propargyl
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-107453-10 mM * 1 mL |
| CAS # | 1862237-99-7 |
| Pricing | 10 mM * 1 mL, USD $605.0 |
| Biological Activity | SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2[1]. |
| Synonyms | PROTAC Sirt2-binding moiety 1 |
| MWt | 424.54 |
| Formula | C₂₁H₂₀N₄O₂S₂ |