Ro60-0175 free base
Ro60-0175 is a potent and selective SR-2 agonist. It shows selectivity for the 5-HT2C subtype (pKi values are 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively). Ro60-0175 acts as a potent and selective agonist for both the 5-HT2B and 5-HT2C serotonin receptor subtypes, with good selectivity over the closely related 5-HT2A subtype, and little or no affinity at other receptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD340 |
| CAS # | 169675-08-5 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | Ro60-0175; Ro-60-0175; Ro 60-0175; Ro600175; Ro-600175; Ro 600175; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C11H12ClFN2 |
| Exact Mass | 226.0673 |
| Molecular Weight | 226.6794 |
| Elemental Analysis | C, 58.29; H, 5.34; Cl, 15.64; F, 8.38; N, 12.36 |
| IUPAC/Chemical Name | (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine |
| InChi Key | XJJZQXUGLLXTHO-ZETCQYMHSA-N |
| InChi Code | InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1 |
| SMILES Code | C[C@H](N)CN1C=CC2=C1C=C(Cl)C(F)=C2 |
| Appearance | To be determined |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |