Kenpaullone
Supplier | MedChemExpress |
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Product # | HY-12302-10 mM * 1 mL |
CAS # | 142273-20-9 |
Pricing | 10 mM * 1 mL, USD $92.0 |
Biological Activity | Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β, with IC50s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC50s of 0.68 μM, 7.5 μM, 0.85 μM, respectively. Kenpaullone, a small molecule inhibitor of KLF4, reduces self-renewal of breast cancer stem cells and cell motility in vitro. |
Synonyms | 9-Bromopaullone; NSC-664704 |
MWt | 327.18 |
Formula | C₁₆H₁₁BrN₂O |