Conoidin A
Supplier | MedChemExpress |
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Product # | HY-116090-10 mM * 1 mL |
CAS # | 18080-67-6 |
Pricing | 10 mM * 1 mL, USD $55.0 |
Biological Activity | Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 µM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII)[1][2]. Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease[3]. |
Purity | 98.03% |
MWt | 347.99 |
Formula | C₁₀H₈Br₂N₂O₂ |