Rosuvastatin D3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-17504AS-1 mg |
| CAS # | 1133429-16-9 |
| Pricing | 1 mg, USD $220.0 |
| Biological Activity | Rosuvastatin D3 (ZD 4522 D3) is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM[1]. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals[2]. |
| Synonyms | ZD 4522 D3 |
| MWt | 484.56 |
| Formula | C₂₂H₂₅D₃FN₃O₆S |