KG 5
KG 5 is a B-Raf allosteric and PDGFRβ inhibitor. It inhibits FLT3, KIT and c-Raf. It arrests cells in prometaphase and inhibits growth of renal and pancreatic tumors in mice. It also inhibits angiogenesis in a mouse angiogenesis model and disrupts blood vessel formation in zebrafish embryos. It is orally available.
| Supplier | BOC Sciences |
|---|---|
| Product # | 877874-85-6 |
| Pricing | Inquire |
| Cas | 877874-85-6 |
| Molecular Weight | 459.45 |
| Molecular Formula | C20H16F3N7OS |
| Canonical SMILES | CSC1=NC(=CC(=N1)OC2=CC=C(C=C2)C3=NC(=NN3)NC4=CC=CC(=C4)C(F)(F)F)N |