GMP synthase (glutamine-hydrolysing)

Involved in the de novo biosynthesis of guanosine nucleotides. An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain. The enzyme can catalyse the second reaction alone in the presence of ammonia.

• Supplier: Creative Enzymes
• Product #: EXWM-5805
• CAS: 37318-71-1