JNJ-10181457 dihydrochloride
JNJ-10181457 is an antagonist of histamine H3 receptors that increases extracellular norepinephrine and acetylcholine levels in the frontal cortex.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD264 |
| CAS # | 544707-20-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | JNJ-10181457; RWJ 662733 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C20H30Cl2N2O |
| Molecular Weight | 385.373 |
| Elemental Analysis | C, 62.33; H, 7.85; Cl, 18.40; N, 7.27; O, 4.15 |
| IUPAC/Chemical Name | 4-[[3-[4-(1-piperidinyl)-1-butyn-1-yl]phenyl]methyl]-morpholine, dihydrochloride |
| InChi Key | HDRIBIYPLKZUDQ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C20H28N2O/c1-3-10-21(11-4-1)12-5-2-7-19-8-6-9-20(17-19)18-22-13-15-23-16-14-22/h6,8-9,17H,1,3-5,10-16,18H2 |
| SMILES Code | N1(CC2=CC=CC(C#CCCN3CCCCC3)=C2)CCOCC1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |