Aurora kinase inhibitor-3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112373-5 mg |
| CAS # | 879127-16-9 |
| Pricing | 5 mg, USD $350.0 |
| Biological Activity | Aurora kinase inhibitor-3 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50 of >10 μM. Aurora kinase inhibitor-3 has a binding mode with the cyclopropanecarboxylic acid moiety directed towards the solvent exposed region of the ATP-binding pocket[1]. |
| Purity | 98.98% |
| MWt | 413.4 |
| Formula | C₂₁H₁₈F₃N₅O |