phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase

This enzyme hydroylses 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. The enzyme also shows activity toward (PtdIns(1,3,4,5)P4). The enzyme is involved in several signal transduction pathways in the immune system leading to an adverse range of effects.
Supplier Creative Enzymes
Product # EXWM-3692
Pricing 100 ug, contact supplier for pricing
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