PROTAC RAR Degrader-1

PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs).
Supplier BOC Sciences
Product # 1351169-27-1
Pricing Inquire
Cas 1351169-27-1
Molecular Weight 917.14
Molecular Formula C51H72N4O11
Canonical SMILES O=C(O)C1=CC=C(C=CC(=O)C=2C=C(C=C(C2)C(C)(C)C)C(C)(C)C)C=C1OCCCNC(=O)COCCOCCOCCNC(=O)C(NC(=O)C(O)C(N)CC=3C=CC=CC3)CC(C)C
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