Human Anti-FGFR3 Recombinant Antibody (clone Antibody 1); scFv Fragment
Full length FGFR-3 has two splice forms called FGFR-3(IIIb) and FGFR-3(IIIc) that result from alternative exons encoding the third IgG-like domain of FGFR-3. FGFR-3 also has well documented mutant forms due to errors in DNA replication or translation. Given the active role of the FGFR-3 signaling pathway in a wide range of diseases including cancer, there is a need for a mechanism by which to regulate this pathway. Provided is an isolated antibody, which specifically binds to human FGFR-3(IIIb) and FGFR-3(IIIc), or mutant forms thereof.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-0159-YC-S(P) |
| Pricing | Inquiry |
| Host | Human |
| Target | FGFR3 |
| Species Reactivity | Human, Mouse |
| Type | Human scFv |
| Applications | ELISA, FuncS |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |