Leptomycin A
Supplier | MedChemExpress |
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Product # | HY-N6795 |
CAS # | 87081-36-5 |
Pricing | inquire |
Biological Activity | Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B[1][2]. |
MWt | 526.7 |
Formula | C₃₂H₄₆O₆ |