Leptomycin A

Supplier MedChemExpress
Product # HY-N6795
CAS # 87081-36-5
Pricing inquire
Biological Activity Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B[1][2].
MWt 526.7
Formula C₃₂H₄₆O₆
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