Agomelatine
Agomelatine (BAN, rINN; trade names Valdoxan, Melitor, Thymanax) is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder and has been reported to not produce discontinuation syndrome and have no sexual side effects compared to SSRIs, SNRIs and the older tricyclic antidepressants. Agomelatine may also have positive effects on sleep. Agomelatine is a melatonergic agonist (MT1 and MT2 receptors) and 5-HT2C antagonist. Binding studies indicate that it has no effect on monoamine uptake and no affinity for α, β adrenergic, histaminergic, cholinergic, dopaminergic and benzodiazepine receptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD648 |
| CAS # | 138112-76-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | Valdoxan; Thymanax; Melitor; AGO 178; AGO-178; AGO178; N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide; S 20098; S-20098; S20098. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C15H17NO2 |
| Exact Mass | 243.12593 |
| Molecular Weight | 243.31 |
| Elemental Analysis | C, 74.05; H, 7.04; N, 5.76; O, 13.15 |
| IUPAC/Chemical Name | N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide |
| InChi Key | YJYPHIXNFHFHND-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17) |
| SMILES Code | CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Autism |
| Availability | 2 Weeks |