Taccalonolide A
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-N2416-5 mg |
| CAS # | 108885-68-3 |
| Pricing | 5 mg, USD $403.0 |
| Biological Activity | Taccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri, with cytotoxic and antimalarial activities[1][2]. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis[1]. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells[3]. |
| MWt | 702.74 |
| Formula | C₃₆H₄₆O₁₄ |