PRMT5-IN-1

Supplier MedChemExpress
Product # HY-126256
CAS # 2366149-83-7
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Biological Activity PRMT5 IN-1, a hemiaminal, is a covalent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 11 nM for PRMT5/MEP50. PRMT5 IN-1 can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions[1].
MWt 418.83
Formula C₁₉H₁₉ClN₄O₅
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