L-Buthionine-(S,R)-sulfoximine
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-106376A-10 mM * 1 mL |
| CAS # | 83730-53-4 |
| Pricing | 10 mM * 1 mL, USD $66.0 |
| Synonyms | L-Buthionine sulfoximine; L-BSO |
| MWt | 222.31 |
| Formula | C₈H₁₈N₂O₃S |
| Biological Activity | L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively. |
| Purity | ≥98.0% |