Almorexant
Almorexant, also known as ACT-078573, is a competitive receptor antagonist of the OX1 and OX2 orexin receptors. Almorexant selectively inhibits the functional consequences of OX1 and OX2 receptor activation, such as intracellular Ca2+ mobilization.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1268 |
| CAS # | 871224-64-5 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | ACT-078573, Almorexant |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C29H31F3N2O3 |
| Exact Mass | 512.2287 |
| Molecular Weight | 512.57 |
| Elemental Analysis | C, 67.95; H, 6.10; F, 11.12; N, 5.47; O, 9.36 |
| IUPAC/Chemical Name | (2R)-2-((1S)-6,7-dimethoxy-1-{2-(4-(trifluoromethyl)phenyl)ethyl}-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide |
| InChi Key | DKMACHNQISHMDN-RPLLCQBOSA-N |
| InChi Code | 1S/C29H31F3N2O3/c1-33-28(35)27(20-7-5-4-6-8-20)34-16-15-21-17-25(36-2)26(37-3)18-23(21)24(34)14-11-19-9-12-22(13-10-19)29(30,31)32/h4-10,12-13,17-18,24,27H,11,14-16H2,1-3H3,(H,33,35)/t24-,27+/m0/s1 |
| SMILES Code | CNC(=O)[C@H](N1CCc2cc(OC)c(OC)cc2[C@@H]1CCc3ccc(cc3)C(F)(F)F)c4ccccc4 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |