Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176)
Recombinant Human Antibody (3BC176) is capable of binding to a broadly neutralizing epitope in the vicinity of the V3 loop and the CD4-induced site and highly complement the neutralization spectrum of potent broadly neutralizing anti-CD4 binding site (CD4bs) antibodies obtained from the same individual, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 gp41 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HIV-1 gp41 mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABL-187 |
| Pricing | Inquiry |
| Host | Human |
| Target | HIV-1 gp41 |
| Species Reactivity | HIV-1 |
| Type | Human IgG |
| Applications | Neut, FuncS |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |