Lurasidone HCl
Lurasidone HCl, also known as SM-13496, is an atypical antipsychotic drug. In the USA since 2013, it is also approved for the treatment of depressive episodes associated with bipolar I disorder as well as bipolar II disorder in adults when used alone or in combination with lithium, valproate, or lamotrigine. Lurasidone may be useful for treating the cognitive and memory deficits seen in schizophrenia. Lurasidone has activity at several serotonin receptors that are involved in learning and memory.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1289 |
| CAS # | 367514-88-3 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | SM-13496; SM 13496; SM13496; Lurasidone HCl. trade name Latuda. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C28H37ClN4O2S |
| Molecular Weight | 529.14 |
| Elemental Analysis | C, 63.56; H, 7.05; Cl, 6.70; N, 10.59; O, 6.05; S, 6.06 |
| IUPAC/Chemical Name | (3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride |
| InChi Key | NEKCRUIRPWNMLK-SCIYSFAVSA-N |
| InChi Code | InChI=1S/C28H36N4O2S.ClH/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26;/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2;1H/t18-,19+,20-,21-,24+,25-;/m0./s1 |
| SMILES Code | O=C1N(C[C@H]2[C@H](CN3CCN(C4=NSC5=C4C=CC=C5)CC3)CCCC2)C([C@]6([H])[C@@](C7)([H])CC[C@@]7([H])[C@]16[H])=O.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Bipolar Disorder |
| Availability | 2 Weeks |