Tandutinib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10202A-10 mM * 1 mL |
| Pricing | 10 mM * 1 mL, USD $66.0 |
| Synonyms | MLN518 hydrochloride; CT53518 hydrochloride |
| MWt | 599.16 |
| Formula | C₃₁H₄₃ClN₆O₄ |
| Biological Activity | Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML)[1][2]. Tandutinib hydrochloride has the ability to cross the blood-brain barrier[3]. |
| Purity | 98.84% |