D-NMAPPD

D-NMAPPD is an inhibitor of ceramidase. It induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner but doesn't have effect on viability of rat hepatocytes, Kupffer cells, or sinusoidal endothelial cells when used at a concentration of 100 mM. It also increases intracellular ceramide accumulation and cytochrome C release and induces apoptosis in SW403 cells.

• Supplier: BOC Sciences
• Product #: 35922-06-6
• Cas: 35922-06-6
• Molecular Weight: 422.6
• Molecular Formula: C23H38N2O5
• Canonical SMILES: CCCCCCCCCCCCCC(=O)NC(CO)C(C1=CC=C(C=C1)[N+](=O)[O-])O