Rosiglitazone hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-17386A |
| CAS # | 302543-62-0 |
| Pricing | inquire |
| Biological Activity | Rosiglitazone hydrochloride (BRL 49653 hydrochloride) is a selective, orally active PPARγ agonist with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively. Rosiglitazone hydrochloride binds to PPARγ with a Kd of approximately 40 nM. Rosiglitazone hydrochloride is also an activator of TRPC5 (EC50=~30 μM) and an inhibitor of TRPM3[1][2][3][4]. |
| Synonyms | BRL 49653 hydrochloride |
| MWt | 393.89 |
| Formula | C₁₈H₂₀ClN₃O₃S |