Recombinant Mouse CD40 Protein, Fc-tagged, Alexa Fluor 488 conjugated

CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
Supplier Creative Biomart
Product # Cd40-325MAF488
Pricing 20ug : USD $798, 50ug : USD $1298, 100ug : USD $1998
Product Category Recombinant Protein
Shipping Country USA
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