Liarozole dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-106019C-1 mg |
| CAS # | 1883548-96-6 |
| Pricing | 1 mg, USD $95.0 |
| Synonyms | R75251 dihydrochloride |
| MWt | 381.69 |
| Formula | C₁₇H₁₅Cl₃N₄ |
| Biological Activity | Liarozole (R75251; R85246) dihydrochloride is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole dihydrochloride inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of RA (IC50=7 μM), resulting in increased tissue levels of RA. Liarozole dihydrochloride shows antitumoral properties[1][2][3]. |
| Purity | ≥99.0% |