THZ-P1-2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-136351-5 mg |
| CAS # | 2058075-45-7 |
| Pricing | 5 mg, USD $450.0 |
| Biological Activity | THZ-P1-2 is a first-in-class and selective PI5P4K inhibitor, with an IC50 of 190 nM for PI5P4Kα. THZ-P1-2 covalently targets cysteines on a disordered loop in PI5P4Kα/β/γ. THZ-P1-2 causes autophagy disruption and upregulates TFEB signaling. THZ-P1-2 displays anticancer activity in leukemia cell lines[1]. |
| Purity | 99.06% |
| MWt | 531.61 |
| Formula | C₃₁H₂₉N₇O₂ |