Framycetin sulfate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-17624A |
| CAS # | 4146-30-9 |
| Pricing | inquire |
| Biological Activity | Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections[1][2]. |
| Synonyms | Neomycin B sulfate; Fradiomycin B sulfate |
| MWt | 908.88 |
| Formula | C₂₃H₅₂N₆O₂₅S₃ |