Rat Glutamate Decarboxylase 2 (GAD2) Protein

Glutamate Decarboxylase 2 (GAD2) is a recombinant Rat protein produced in E. coli using Prokaryotic expression. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

• Supplier: Abbexa Ltd.
• Product #: abx066818-100UG
• Conjugation: Unconjugated
• Host: E. coli
• Tested Applications: WB, SDS-PAGE
• UniProt Primary AC: Q05683
• Activity: Not tested
• Dry Ice: No
• Availability: Shipped within 5-12 working days.
• Note:
  • This product is for research use only.
  • Not for human consumption, cosmetic, therapeutic or diagnostic use.