Calcium chloride dihydrate77%

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Calcium chloride occurs as a white or colorless crystalline powder,granules, or crystalline mass, and is hygroscopic (deliquescent).
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Product # PE-0673
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product1 Desiccants
Molecular Formula CaCl2` 2H2O
Molecular Weight 147.0 (for dihydrate)
Applications The main applications of calcium chloride as an excipient relate to its dehydrating properties and, therefore, it has been used as an antimicrobial preservative, as a desiccant, and as an astringent in eye lotions. Therapeutically, calcium chloride injection 11% (as the dihy_x0002_drate form) is used to treat hypocalcemia.
Safety
  • Calcium chloride is used in topical, ophthalmic, and injection preparations. The pure form of calcium chloride is toxic by intravenous, intramuscular, intraperitoneal, and subcutaneous routes, and moderately toxic by ingestion, causing stomach and heart disturbances. It is a severe eye irritant and can cause dermatitis.
  • LD50 (mouse, IP): 0.21 g/kg
  • LD50 (mouse, IV): 0.042 g/kg
  • LD50 (mouse, oral): 1.94 g/kg
  • LD50 (mouse, SC): 0.82 g/kg
  • LD50 (rat, IM): 0.025 g/kg
  • LD50 (rat, IP): 0.26 g/kg
  • LD50 (rat, oral): 1.0 g/kg
  • LD50 (rat, SC): 2.63 g/kg
Incompatibilities Calcium chloride is incompatible with soluble carbonates, phos_x0002_phates, sulfates, and tartrates.It reacts violently with bromine trifluoride, and a reaction with zinc releases explosive hydrogen gas. It has an exothermic reaction with water, and when heated to decomposition it emits toxic fumes of chlorine.
Synonyms Calcii chloridum dihydricum; calcii chloridum hexahydricum.
CAS Number 10035-04-8
Category
  • Antimicrobial preservative; therapeutic agent; water-absorbing
  • agent.
UNII M4I0D6VV5M
Chemical Name Calcium chloride dihydrate
Grade Pharmaceutical grade
Administration route Infiltration,Intramuscular,Intraocular,Intrathecal,Intravenous,Intravitreal,Ophthalmic,oral,Respiratory(Inhalation)
Dosage Form Injection,Soultion,Injectable,Liposomal,Susupension, Drops, Capsule,Concentrate
Stability and Storage Conditions Calcium chloride is chemically stable; however, it should be protected from moisture. Store in airtight containers in a cool, dry place.
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