K-252b
A staurosporine analogue isolated from a nocardiopsis strain; a potent inhibitor of protein kinase C. K-252b exhibits potent antitumour activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents; also active against other kinases, notably myosin light chain kinase, camp-dependent protein kinase (PKA), protein kinase C (PKC) and cgmp-dependent protein kinase (PKG).
| Supplier | BOC Sciences |
|---|---|
| Product # | BBF-03705 |
| Pricing | Inquire |
| Cas | 99570-78-2 |
| Molecular Weight | 453.45 |
| Molecular Formula | C26H19N3O5 |
| Canonical SMILES | CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O |