R 59-022
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-107613-10 mM * 1 mL |
| CAS # | 93076-89-2 |
| Pricing | 10 mM * 1 mL, USD $354.0 |
| Synonyms | DKGI-I; Diacylglycerol kinase inhibitor I |
| MWt | 459.58 |
| Formula | C₂₇H₂₆FN₃OS |
| Biological Activity | R 59-022 (DKGI-I) is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 is a 5-HTR antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4]. |
| Purity | ≥99.0% |