CD59 Glycoprotein (CD59) Antibody

CD59 Antibody is a Rabbit Polyclonal antibody against CD59. This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
Supplier Abbexa Ltd.
Product # abx001417-50UL
Pricing 50 µl USD $319.0
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications WB, IHC
UniProt Primary AC P13987
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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