ACT-335827
ACT-335827 is a potent and selective orexin OX1 receptor antagonist. Orexin contributes to the expression of the cardiovascular and behavioural response of some forms of stress, including novelty stress.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD075 |
| CAS # | 1354039-86-3 |
| Pricing | Customizable size, Inquiry |
| Synonym | ACT-335827; ACT 335827; ACT335827; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C31H38N2O5 |
| Exact Mass | 518.2781 |
| Molecular Weight | 518.65 |
| Elemental Analysis | C, 71.79; H, 7.39; N, 5.40; O, 15.42 |
| IUPAC/Chemical Name | (R)-2-((S)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-isopropyl-2-phenylacetamide |
| InChi Key | HXHOBPVRRPCTLG-SETSBSEESA-N |
| InChi Code | InChI=1S/C31H38N2O5/c1-20(2)32-31(34)30(22-10-8-7-9-11-22)33-15-14-23-18-28(37-5)29(38-6)19-24(23)25(33)16-21-12-13-26(35-3)27(17-21)36-4/h7-13,17-20,25,30H,14-16H2,1-6H3,(H,32,34)/t25-,30+/m0/s1 |
| SMILES Code | COC1=CC=C(C[C@H]2C(C=C(OC)C(OC)=C3)=C3CCN2[C@H](C4=CC=CC=C4)C(NC(C)C)=O)C=C1OC |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.03.00 |
| Availability | 2 Weeks |