BMX-IN-1

Supplier MedChemExpress
Product # HY-80002-10 mM * 1 mL
CAS # 1431525-23-3
Pricing 10 mM * 1 mL, USD $196.0
Synonyms BMX kinase inhibitor
MWt 524.59
Formula C₂₉H₂₄N₄O₄S
Biological Activity BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
Purity 99.04%
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