LY-2624803
LY2624803 is a 5-HT2A and histamine H1 receptor antagonist from Eli Lilly as part of its product line-up for therapeutics for the central nervous system. LY2624803 is in phase 2 of clinical trials for the treatment of chronic insomnia. LY2624803 has specific histamine and serotonin receptor antagonism and does not produce other unwanted side effects and it also penetrates into the brain well.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1282 |
| CAS # | 879409-35-5 |
| Pricing | Customizable size, Inquiry |
| Synonym | LY-2624803; HY-10275; LY2624803; DB-7; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C22H25N3O3 |
| Exact Mass | 379.1896 |
| Molecular Weight | 379.46 |
| Elemental Analysis | C, 69.64; H, 6.64; N, 11.07; O, 12.65 |
| IUPAC/Chemical Name | 1-Piperazinepropanoic acid, 4-dibenz(b,f)(1,4)oxazepin-11-yl-alpha,alpha-dimethyl- |
| InChi Key | UEFWDVMEDFCHGW-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C22H25N3O3/c1-22(2,21(26)27)15-24-11-13-25(14-12-24)20-16-7-3-5-9-18(16)28-19-10-6-4-8-17(19)23-20/h3-10H,11-15H2,1-2H3,(H,26,27) |
| SMILES Code | O=C(O)C(C)(C)CN1CCN(C2=NC3=CC=CC=C3OC4=CC=CC=C24)CC1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |