Aluminum Phosphate Adjuvant
Aluminum phosphate adjuvant is a white hydrogel that sediments slowly and forms a clear supernatant.
| Supplier | CD Formulation |
|---|---|
| Product # | PE0379 |
| Pricing | , Inquire for price |
| product1 | Pharmaceutical Excipients |
| Molecular Formula | Al(OH)x(PO4)y |
| Applications | Aluminum phosphate adjuvant is used in parenteral human and veterinary vaccines. |
| Safety | Aluminum phosphate adjuvant is intended for use in parenteral vaccines and is generally regarded as safe. It may cause mild irritation, dryness, and dermatitis on skin contact. It may also cause redness, conjunctivitis, and short-term mild irritation on eye contact. Ingestion of large amounts of aluminum phosphate adjuvant may cause respiratory irritation with nausea, vomiting, and constipation. Inhalation is unlikely, although the dried product may cause respiratory irritation and cough. Type I hypersensitivity reactions following parenteral administration have also been reported. |
| Incompatibilities | The point of zero charge is related directly to the Al : P atomic ratio.Therefore, the substitution of additional phosphate groups for hydroxyl groups will lower the point of zero charge. Substitution of carbonate, sulfate, or borate ions for hydroxyl groups will also lower the point of zero charge. |
| Synonyms | Adju-Phos; aluminum hydroxyphosphate; aluminium hydroxyphosphate; Rehydraphos. |
| Category | Adsorbents |
| Chemical Name | Aluminum phosphate |
| Grade | Pharmceutical Excipients |
| Stability and Storage Conditions | Aluminum phosphate adjuvant is stable fwhen stored at 4-30℃ in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged. |