Carisbamate
Carisbamate, also known as JNJ-10234094, RWJ 333369 and YKP-509, is an antiepileptic candidate. Carisbamate has powerful disease-modifying effects in the lithium-pilocarpine model of temporal lobe epilepsy. Carisbamate inhibits glutamate transmission in the granule cell of the dentate gyrus. Carisbamate acutely suppresses spasms in a rat model of symptomatic infantile spasms.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD699 |
| CAS # | 194085-75-1 (S-isomer) |
| Pricing | Customizable size, Inquiry |
| Synonym | JNJ-10234094; JNJ10234094; JNJ10234094; RWJ 333369; RWJ333369; RWJ-333369; YKP-509; YKP-509; YKP-509; Carisbamate. trade name Comfyde. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C9H10ClNO3 |
| Exact Mass | 215.0349 |
| Molecular Weight | 215.633 |
| Elemental Analysis | C, 50.13; H, 4.67; Cl, 16.44; N, 6.50; O, 22.26 |
| IUPAC/Chemical Name | (S)-2-(2-chlorophenyl)-2-hydroxyethyl carbamate |
| InChi Key | OLBWFRRUHYQABZ-MRVPVSSYSA-N |
| InChi Code | InChI=1S/C9H10ClNO3/c10-7-4-2-1-3-6(7)8(12)5-14-9(11)13/h1-4,8,12H,5H2,(H2,11,13)/t8-/m1/s1 |
| SMILES Code | O[C@@H](C1=CC=CC=C1Cl)COC(N)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |