OMS-824
OMS-824 is a phosphodiesterase-10 (PDE10) inhibitor that slows or stops the hydrolysis of cAMP and cGMP. As PDE10 is found prominently in the caudate nucelus, it is a promising target of OMS-824 in treating Alzheimer's, schizophrenia, and Huntington's diseases.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1607 |
| CAS # | 1207549-69-6 |
| Pricing | Customizable size, Inquiry |
| Synonym | OMS-824; OMS 824; OMS824 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C21H21BrN4O4 |
| Exact Mass | 472.0746 |
| Molecular Weight | 473.33 |
| Elemental Analysis | C, 53.29; H, 4.47; Br, 16.88; N, 11.84; O, 13.52 |
| IUPAC/Chemical Name | (E)-2-(4-(1H-pyrazol-1-yl)phenyl)-N'-(4-bromo-3,5-dimethoxybenzylidene)-2-methoxyacetohydrazide |
| InChi Key | YPIBFZQJCQFGFY-YDZHTSKRSA-N |
| InChi Code | InChI=1S/C21H21BrN4O4/c1-28-17-11-14(12-18(29-2)19(17)22)13-23-25-21(27)20(30-3)15-5-7-16(8-6-15)26-10-4-9-24-26/h4-13,20H,1-3H3,(H,25,27)/b23-13+ |
| SMILES Code | O=C(N/N=C/C1=CC(OC)=C(Br)C(OC)=C1)C(C2=CC=C(N3N=CC=C3)C=C2)OC |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |