Temuterkib (LY3214996)
Temuterkib (LY3214996) is a selective and novel ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. It potently inhibits cellular phospho-RSK1 in BRAF and RAS mutant cancer cell lines.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S8534 |
| Sku # | S8534-5mg |
| Pricing | 5mg, $270.00 |
Citations for this product:
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bioRxiv - Cancer Biology 2023Quote: ... Vx-11e and Temuterkib (S2673, S1078, S1555, S1460, S7709, S8534, Selleck Chemicals). Supernatants were collected to determine the secreted GM-CSF levels ...