FNDR-20123 free base
FNDR-20123 is a first-in-class, and orally active anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50 = 41 nM) and sexual blood stage (IC50 = 190 nM for male gametocytes).
Supplier | BOC Sciences |
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Product # | 1267502-34-0 |
Pricing | Inquire |
Cas | 1267502-34-0 |
Molecular Weight | 377.44 |
Molecular Formula | C21H23N5O2 |
Canonical SMILES | C1CCN(C1)CC2=CC=C(C=C2)C3=CN(N=N3)CC4=CC=C(C=C4)C(=O)NO |